Publications

Z. Na, Y. Luo, A. Khitun, J. A. Schofield, S. Smelyansky, S. Muthukumar, E. Valkov, M. D. Simon, S. A. Slavoff. “The NBDY microprotein regulates cellular RNA decapping and phase separation.” Submitted.

Y. Luo, J. Schofield, Z. Na, M. D. Simon, S. A. Slavoff. “Discovery of cellular substrates of human RNA decapping enzyme Dcp2 using a stapled bicyclic peptide inhibitor.” ChemRxiv.

X. Cao, A. Khitun, Z. Na, T. Phoodokmai, K. Sappakhaw, E. Olatunji, C. Uttamapinant, S. A. Slavoff. “Alt-RPL36 downregulates the PI3K-AKT-mTOR signaling pathway by interacting with TMEM24.” BioRxiv.

X. Cao, A. Khitun, Z. Na, D. Dumitrescu, M. Kubica, E. Olatunji, S. A. Slavoff. “Comparative proteomic profiling of unannotated microproteins and alternative proteins in human cell lines.” Journal of Proteome Research2020, early online.

Y. Luo, J. Schofield, M. D. Simon, S. A. Slavoff. “Global profiling of cellular substrates of human Dcp2.” Biochemistry, 2020early online.

X. Cao, S. A. Slavoff. “Non-AUG start codons: Expanding and regulating the small and alternative ORFeome.” Experimental Cell Research, 2020, 391(1), 111973. Full Text

R. M. Brecht, C. C. Liu, H. A. Beilinson, A. Khitun, S. A. Slavoff, D. G. Schatz. “Nucleolar localization of RAG1 modulates V(D)J recombination activity.” Proceedings of the National Academy of Sciences, 2020, 117(8):4300-4309. Full Text

A. Khitun, S. A. Slavoff. “Proteomic detection and validation of translated small open reading frames.” Current Protocols in Chemical Biology, 2019, 11(4):e77. Full Text

A. Khitun, T. Ness, S. A. Slavoff. “Small open reading frames and cellular stress responses.” Molecular Omics, 2019, 15(2):108-116. Full Text

R. Jackson, L. Kroehling, A. Khitun, W. Bailis, A. Jarret, A. G. York, O. M. Khan, J. R. Brewer, M. H. Skadow, C. Duizer, C. C. D. Harman, L. Chang, P. Bielecki, A. G. Solis, H. R. Steach, S. Slavoff, R. A. Flavell. “The translation of non-canonical open reading frames controls mucosal immunity.” Nature2018, 564(7736):434-438. Full Text

Y. Luo, Z. Na, S. A. Slavoff. “P-bodies: composition, properties and functions.” Biochemistry, 201857(17): 2424-2431. Full Text

R. Aebersold et al. “How many human proteoforms are there?” Nature Chemical Biology201814(3):206-214. Full Text

P. Yuan, N. G. D’Lima, S. A. Slavoff. “Comparative membrane proteomics reveals a nonannotated E. coli heat shock protein.” Biochemistry, 2018, 57, 56-69. Full Text

N. G. D’Lima, A. Khitun, A. D. Rosenbloom, P. Yuan, B. M. Gassaway, K. W. Barber, J. Rinehart, S. A. Slavoff. “Comparative proteomics enables identification of nonannotated cold shock proteins in E. coli.” Journal of Proteome Research, 2017, 13, 3722-3731. Full Text

N. G. D’Lima, J. Ma, L. Winkler, Q. Chu, K. H. Loh, E. O. Corpuz, B. A. Budnik, J. Lykke-Andersen, A. Saghatelian, S. A. Slavoff. “A human microprotein that interacts with the mRNA decapping complex.” Nature Chemical Biology, 2017, 13, 174–180Full Text

Selected Pre-Yale publications

S. A. Slavoff, J. Heo, B. A. Budnik, L. Hanakahi, A. Saghatelian. “A human short open reading frame (sORF)-encoded polypeptide that stimulates DNA end joining.” Journal of Biological Chemistry, 2014, 289, 10950-10957.

J. Ma, C. C. Ward, I. Jungreis, S. A. Slavoff, A. G. Schwaid, J. Neveu, B. A. Budnik, M. Kellis, A. Saghatelian. “The discovery of human sORF-encoded polypeptides (SEPs) in cell lines and tissue.” Journal of Proteome Research, 2014, 13, 1757–1765.

S. A. Slavoff, A. J. Mitchell, A. G. Schwaid, M. N. Cabili, J. Ma, J. Z. Levin, A. D. Karger, B. A. Budnik, J. L. Rinn, A. Saghatelian. “Peptidomic discovery of short open reading frame-encoded peptides in human cells.” Nature Chemical Biology, 2013, 9, 59-64.

S. A. Slavoff, D. S. Liu, J. D. Cohen, A. Y. Ting. “Imaging protein-protein interactions inside living cells via interaction-dependent fluorophore ligation.” Journal of the American Chemical Society, 2011, 133, 19769–19776.

S. A. Slavoff, I. Chen, Y. A. Choi, A. Y. Ting. “Expanding the substrate tolerance of biotin ligase through exploration of enzymes from diverse species.” Journal of the American Chemical Society, 2008, 130, 1160-1162.