Chemical tools to study RNA and microproteins

Welcome! We are a young lab in the Yale Chemical Biology Institute. We are developing chemical and biological tools to study translation of small open reading frames, the functions of their encoded microproteins, and the spatiotemporal regulation of RNA degradation in human cells. We utilize a broad range of interdisciplinary methods, including mass spectrometry-based proteomics, cellular imaging, chemical synthesis, and small molecule-mediated control of biomolecular function. To learn more…


November 14, 2018
We receive a career development award from the Yale Skin Cancer SPORE for collaborative work on new strategies to combat melanoma. Thanks to the Skin Cancer SPORE and the NIH...
June 7, 2018
Two great undergraduate research assistants are joining us for the summer, Kenny Wang (Yale ‘20) and Susanna Barrett (Scripps College ‘19). They’re both working on...
February 26, 2018
Jessica Yuan successfully defended her thesis today to become our first Ph.D. graduate! Congratulations, Jessica, and best of luck for your future.