September 19, 2023
Out today at Cell Reports, Yanran, Xiongwen, Haomiao and Kevin describe EMBOW, an unannotated microprotein that binds to WDR5 with far-reaching cellular consequences. The biggest takeaway from this story is that microproteins can interact with important drug targets, so we may need to consider them in mechanism-of-action studies in the future. Congratulations, all!